Abstract
Summary
We present DETECT v2—an enzyme annotation tool which considers the effect of sequence diversity when assigning enzymatic function [as an Enzyme Commission (EC) number] to a protein sequence. In addition to capturing more enzyme classes than the previous version, we now provide EC-specific cutoffs that greatly increase precision and recall of assignments and show its performance in the context of pathways.
Availability and implementation
Supplementary information
Supplementary data are available at Bioinformatics online.
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2018
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